Pertussis-known colloquially as whooping cough- is the most common vaccine-preventable bacterial disease found in humans, and despite the long-standing, widespread availability of an effective vaccine, it appears to be increasing in incidence in much of the world, including North America and Europe.  This increase in incidence can be attributed to the fact that immunity from vaccination [in children] tends to wane over about 5-10 years and has transformed the major route of transmission of pertussis from a child-to-child or infant-to-infant pattern to one of adolescent (or adult) to susceptible infant--especially to those infants who have not yet received initial immunization--and also transmission among adolescents and adults.

At the conclusion of this enduring material, learners should be able to:

  • discuss the epidemiology of pertussis including the incidence by age group in St. Louis County based on the existing St. Louis County public health data
  • recall the likelihood of pertussis among adolescents and adults with chronic cough and differential diagnosis
  • identify other clinical characteristics of the disease in adolescents and adults
  • compute that adults serve as the primary reservoir of the organisms that infect children,  particularly young children
  • list diagnostic tests (PCR and culture) including sensitivity and specificity as a function of duration of illness
  • conduct the techniques for obtaining samples (nasopharyngeal swabbing)
  • state the availability of Tdap vaccine and the CDC recommendations for adolescents and adults

Faisal Khan, MBBS, MPH
Director, Division of Communicable Disease Control Svcs
Saint Louis County Department of Health

 Rebmann Terri Rebmann, PhD, RN, CIC
Associate Professor
Institute for Biosecurity
School of Public Health
Saint Louis University
Zelicoff Alan Zelicoff, MD
Professor of Epidemiology & Environmental & Occupational Health
School of Public Health
Saint Louis University

Contributing Authors
 Karla Howell, RN
 Ayesha Iqbal, MBBS, MPH
 Faisal Khan, MBBS, MPH
 Richard Knaup
 Janelle Leighton, RN, BSN
 Eleanor Peters, MSPH, MA
 Sarah Patrick,MPH, PhD
 Terri Rebmann, PhD, RN, CIC
 Alan Zelicoff, MD

Contributing Students
Waqas Humayon
Eric Klick

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education through the joint providership of
Saint Louis University School of Medicine, Saint Louis University School of Public Health, and Saint Louis County Health.  Saint Louis University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

American Medical Association
Saint Louis University School of Medicine designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™.  Physicians should only claim credit commensurate with the extent of their participation in the activity.      
This CME was made possible by an educational grant from Sanofi Pasteur US

Sanofi Pasteur
This activity was planned and implemented through the  joint providership of:

Saint Louis County Health   Saint Louis University School of Public Health:  Institute for BIOSecurity

Saint Louis University School of Medicine


Enduring Material is Approved for the following time-frame:
August 1, 2012 through August 31, 2015

Completion of this enduring material will take approximately 60 minutes.

Software/Computer Requirements:
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Completion Requirements  this Enduring Material:

(1.) Complete the pre-test questions
(2.) View the enduring material video
(3.) Complete and pass the post-test with 80% or higher
(4.) Complete the evaluation

Note: Re-take of the post-test is available up to three attempts.

Once the above required steps are completed you will be provided with a link to download your CME/CE certificate.

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